National Cancer Institute

Comprehensive Research Effort Advanced on Tobacco Use
19 Nov 98 | The National Cancer Institute (NCI), following the recommendations of its Tobacco Research Implementation Group, is advancing a plan to expand and accelerate tobacco research that can prevent cancers associated with tobacco use. These priorities ...

NCI Continues to Conduct Research on Endostatin and Angiostatin
12 Nov 98 | People interested in information about ongoing trials listed in NCI's PDQ database may contact NCI's Cancer Information Service at 1-800-4-CANCER or search PDQ themselves via the Internet (http://cancertrials.nci.nih.gov -- under Special Features,...

Questions and Answers: New Findings About Interferon Therapy for Melanoma
09 Nov 98 | This clinical trial compared interferon alpha-2b -- both high-dose and low-dose interferon alpha-2b -- to no additional treatment after surgery for patients with melanoma at high risk for recurrence. E1690 found that patients who received high-...

Informed Consent: New Recommendations Aim to Simplify Documents, Improve Quality
22 Oct 98 | The National Cancer Institute (NCI) has unveiled new recommendations for informed consent documents that aim to make the forms more understandable and more useful to people who are considering participation in a cancer clinical trial. In a mailing...

Study of Tamoxifen and Raloxifene To Open in Early 1999
21 Oct 98 | All 22,000 postmenopausal women at increased risk of breast cancer who participate in STAR will receive a drug that could reduce their chance of developing breast cancer. STAR builds upon the success of the Breast Cancer Prevention Trial (BCPT), ...

With Herceptin® Now Available, Registration Ends for NCI's Expanded Access Program
06 Oct 98 | SPOC also manages the company's Patient Assistance Program which provides access for uninsured patients. The expanded access program has made Herceptin available to patients with metastatic breast cancer who did not meet the criteria for other ...

Unconventional Innovations Program
06 Oct 98 | To spur development of daring technologic improvements in cancer treatment and detection in the 21st century, the National Cancer Institute (NCI) recently created an Unconventional Innovations Program. The ultimate goal of the program is to ...

Scientists Report New Lead in the Regulation of HIV Coreceptor
06 Oct 98 | M-tropic virus, conversely, uses the CCR5 protein as its coreceptor, marking a key difference in how the two strains infect cells. Studies indicate that after Langerhans cells become infected with M-tropic virus, they migrate to the lymph nodes, ...

Clinical Trials and Informatics
06 Oct 98 | The National Cancer Institute (NCI) is reforming its clinical trials program to make both cancer information and the trials themselves more accessible to all Americans. It will make accrual of patients to trials faster, help harmonize ...

Estimating Breast Cancer Risk
06 Oct 98 | This fact sheet provides information on the Breast Cancer Risk Assessment Tool and about breast cancer risk and the drug tamoxifen. 2. What are the risk factors used to estimate breast cancer risk in the Breast Cancer Risk Assessment Tool?

Speeding Drug Discovery with the Chemistry-Biology Centers Program
05 Oct 98 | To further this fast-forward drug screening, the National Cancer Institute recently awarded $5.5 million to create Chemistry-Biology Centers at Harvard University; the University of Pittsburgh; Torrey Pines Institute for Molecular Studies in San ...

Scientist Report New Strategy To Rapidly Assess Effectiveness of AIDS Drugs in Children
01 Oct 98 | In a study of the anti-viral drug ritonavir involving 41 HIV-positive children, the scientists found that by performing a range of tests earlier than is now standard, they could reliably predict within a week of starting the therapy whether or not...

NCI Awards $15 Million to Study Cancer Survivors
30 Sep 98 | University of California - Los Angeles, Los Angeles, Calif.Title: Psychological well-being in long-term cancer survivorsPrincipal investigator: Beth Leedham, Ph.D.Term: July 1, 1998 - June 30, 2000 First-year amount: $42,000 Description: Mental ...

Pilot of Computerized Breast Cancer Risk Assessment Tool Begins, Health Professionals Targeted
29 Sep 98 | A computer-based tool that allows health professionals to project a woman's individualized estimate of breast cancer risk is now available from the National Cancer Institute (NCI). While the tool helps health care providers advise women at ...

Herceptin's FDA Approval Means Drug Will Soon Be Available, Registration Will End for NCI's Expanded Access Program
29 Sep 98 | Registration of new patients on the National Cancer Institute's (NCI's) expanded access trials with Herceptin will end on the day the drug is launched commercially. Eligible patients, selected through the lottery, could enroll in this study at ...

Herceptin® Lottery Ends, Trials Expand to Include More Eligible Patients
22 Sep 98 | The National Cancer Institute (NCI) has announced that Genentech has increased the supply of Herceptin® enough to end the lottery for access to the drug through an NCI study. Until that happens, NCI — working with Genentech and the FDA — is ...

Breast Cancer Prevention Trial Results Published
14 Sep 98 | In this trial, healthy women assigned to take tamoxifen developed 89 cases of invasive breast cancer compared to 175 cases in the women assigned to the placebo. The BCPT was designed to see whether the drug tamoxifen prevents breast cancer in ...

Cooperative Family Registry for Colorectal Cancer Studies
10 Sep 98 | RegistriesNCI now supports six primary registries of familial colon cancer located throughout the world. The six registries, in collaboration with scientists affiliated with other research institutions, will assemble and maintain comprehensive ...

Network Launched to Support Studies of Genetic Susceptibility to Cancer
03 Sep 98 | The National Cancer Institute (NCI) announced today it has awarded cooperative agreements for the new Cancer Genetics Network, a major research initiative to create a national network of centers specializing in the study of inherited ...

Increase in Childhood Brain Tumors Likely Due to Better Diagnosis and Reporting: Incidence Rise Coincides with Spread of Magnetic Resonance Imaging
01 Sep 98 | The reported rise in the incidence of brain tumors in American children is most likely a result of better diagnosis and reporting rather than a true increase in cases, according to analyses by National Cancer Institute (NCI) researchers published ...

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