National Cancer Institute

Questions and Answers: Gleevec
10 May 01 | Gleevec, also known as STI571, is a new drug that the Food and Drug Administration approved today for the treatment of chronic myeloid leukemia (CML), a cancer of white blood cells. By blocking the abnormal protein, called BCR-ABL, Gleevec kills ...

FDA Approves Important New Leukemia Drug Offers Further Proof of Principle for Molecular Targeting in Cancer Treatment
10 May 01 | The U.S. Food and Drug Administration (FDA) announced today its approval of the drug Gleevec as an oral treatment for chronic myelogenous leukemia (CML). Other molecular-targeting drugs previously approved by the FDA interfere with proteins ...

NCI-Sponsored Trial Tests Shark Cartilage Extract in Patients with Non-Small Cell Lung Cancer
09 May 01 | The National Cancer Institute (NCI) has launched a large, randomized clinical trial to test the effects of shark cartilage in combination with chemotherapy and radiotherapy in patients with non-small cell lung cancer (NSCLC) that cannot be removed...

The National Cancer Institute Presents Katie Couric with Second Annual Eleanor Nealon Extraordinary Communicators Award at NIH on May 18, 2001
08 May 01 | In recognition of her personal and professional efforts to raise awareness of colorectal cancer and to teach Americans about the disease, Katie Couric has been named the 2001 recipient of the National Cancer Institute's (NCI) Eleanor Nealon ...

NCI/All-Ireland Consortium Announces First Cancer Statistics Report
08 May 01 | The Ireland-Northern Ireland-NCI (National Cancer Institute) Cancer Consortium has announced publication of the first report on cancer statistics for the island of Ireland, a collaborative effort that marks another milestone for the 2-year-old ...

NCI Announces New Research-Based Web Design Guidelines for Improving Health Information Web Sites
03 May 01 | The Research-Based Web Design and Usability Guidelines represent several years of intense effort by NCI to identify Web design-related research and compile a practical set of guidelines. These guidelines, located on NCI's Usability.gov Web site (...

National Cancer Institute Breast Implant Study
01 May 01 | In 1992, researchers at the National Cancer Institute (NCI) initiated a study on the long-term health effects associated with silicone breast implants. - Developing breast cancer; - Developing cancers other than breast; - Dying from all causes of...

Women With Silicone Breast Implants Have No Increased Risk of Death From Most Causes
27 Apr 01 | Previous reports have limited their analyses to mortality from breast cancer and found, as in this report, no increased risk in breast cancer mortality for implant patients compared to the general population. The researchers compared all causes ...

Silicone Breast Implants Not Linked to Most Cancers
24 Apr 01 | Reporting in the April issue of the Annals of Epidemiology*, researchers from the National Cancer Institute (NCI) in Bethesda, Md., found that women with silicone breast implants were not at increased risk for most cancers. In addition, the ...

Best Leads for Prostate Cancer Prevention Appear in April Urology Supplement; Agents, Biomarker Endpoints, Cohorts, and Trial Designs Outlined
09 Apr 01 | The most promising agents to prevent prostate cancer and the most likely biological markers of risk for the disease are just two of the key areas of prostate cancer prevention research highlighted in the supplement to the April issue of the ...

High Response Rate of Hairy Cell Leukemia Patients to Immunotoxin Treatment Raises Hopes
26 Mar 01 | Because stem cells-the progenitors of normal B cells-do not have CD22, any B cells lost in the short-term treatment should be replaced by the patient's untouched stem cells. Kreitman added, "Malignant stem cells- the progenitors of the leukemic ...

Scientists Report New Finding in Development of B Cells
15 Mar 01 | In the early 1990s, scientists reported that IL-10, a signaling protein excreted by activated immune cells, was essential for the maturation of B lymphocytes. The scientists found that all of the cell lines that expressed TIMP-1 also expressed IL...

NCI-Sponsored Trials of Celecoxib for Cancer Prevention
27 Feb 01 | The National Cancer Institute's (NCI) Division of Cancer Prevention is studying the drug celecoxib (CelebrexŰ) for the prevention of cancer in people with precancerous conditions and in people at high risk for second cancers. Epidemiologic ...

NCI Establishes a Mouse Cancer Models Repository and Distribution Facility
22 Feb 01 | The National Cancer Institute (NCI) recently announced the availability of a new resource for the cancer research community, the NCI-MMHCC (Mouse Models of Human Cancers Consortium) Mouse Repository. The Repository, located at NCI's Frederick, Md...

NCI Announces New Program For Cancer Advocates
21 Feb 01 | Consumer Advocates in Research and Related Activities (CARRA) is a new program to match cancer advocates with opportunities to help NCI in its mission to conduct and support cancer research, training, health information dissemination, and other ...

HPV Testing Shows Which Pap Abnormalities Need Attention
20 Feb 01 | Findings from a major, randomized, multicenter study by the National Cancer Institute (NCI) show that HPV testing is highly sensitive in identifying which Pap-detected abnormalities require immediate attention. One objective of ALTS was to ...

Questions and Answers About the ALTS Findings
20 Feb 01 | ALTS, which stands for the ASCUS/LSIL Triage Study, was organized and funded by the National Cancer Institute (NCI), the U.S. government's principal agency for cancer research. The ALTS study looked at three different ways to manage ASCUS and ...

General Motors Teams Up with Cancer Researchers to Take a Step Toward Breast Cancer Prevention
14 Feb 01 | The National Surgical Adjuvant Breast and Bowel Project (NSABP), a National Cancer Institute (NCI)-supported cancer research network, and General Motors Corporation today announced a unique collaboration between business and cancer research. This...

NIH Course on Human Research Protections Goes Online
18 Jan 01 | Developed by the National Cancer Institute (NCI) for the National Institutes of Health (NIH), the web-based course offers continuing medical education (CME) credit for physicians and contact hours for nurses and other members of research teams. ...

No Association Found Between Cellular Phone Use and Risk of Brain Tumors
21 Dec 00 | Researchers at the National Cancer Institute (NCI) found that people who used cellular phones did not have an increased risk of brain tumors compared to non-users. The NCI adult brain tumor study involves about 800 adult brain tumor cases and 800...

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