National Cancer Institute

Questions and Answers About the 6C (Cooperative Colorectal Cancer Combination Chemotherapy Clinical) Trial
30 Jun 99 | The 6C Trial is a study designed to evaluate the effectiveness of several different regimens of drugs as the initial therapy for patients with advanced colorectal cancer. This clinical trial will evaluate two new drugs, oxaliplatin and CPT-11, ...

NCI Will Test New Drugs for Colorectal Cancer Throughout North America
28 Jun 99 | The National Cancer Institute (NCI) is launching a large research study that will test two of the most promising new drugs for metastatic colorectal cancer. Now beginning to enroll about 1,700 patients, the Cooperative Colorectal Cancer ...

Prostate Imaging Treatment Initiative Announced
25 Jun 99 | The ability to diagnose early prostate cancer is not matched by imaging techniques to accurately determine a tumor's location, or markers for aggressiveness. With better imaging, the sparing of normal tissue and controlling damage to normal ...

Scientists Suggest New Approaches for Development of AIDS Drugs and Vaccines
21 Jun 99 | Three years ago this month, scientists made headlines when they discovered that HIV-1 first infects human immune cells by attaching not only to the well known CD4 protein displayed on the cell surface, but also to a second protein receptor called ...

Publication of the MORE Trial Results Supports Study of Tamoxifen and Raloxifene (STAR)
15 Jun 99 | STAR is a study of 22,000 postmenopausal women at increased risk of breast cancer to determine whether raloxifene is as effective in reducing the chance of developing breast cancer as tamoxifen (Nolvadex©) has proven to be. Tamoxifen was shown to...

Questions and Answers: The Study of Tamoxifen and Raloxifene (STAR)
14 Jun 99 | The Study of Tamoxifen and Raloxifene (STAR) is a clinical trial (a research study conducted with volunteers) designed to see how the drug raloxifene (Evista©) compares with the drug tamoxifen (Nolvadex©) in reducing the incidence of breast cancer...

NCI Releases New Human Gene Variation Resource
08 Jun 99 | According to Kenneth Buetow, Ph.D., co-presenter of the data and a member of NCI's Genetic Annotation Initiative (GAI), the gene variations still must be validated. Buetow said NCI has made information on all of the candidate SNPs available to ...

Important Points About the Study of Tamoxifen and Raloxifene (STAR)
25 May 99 | STAR is also the first trial to compare a drug proven to reduce the chance of developing breast cancer with another drug that has the potential to reduce breast cancer risk. Tamoxifen (trade name Nolvadex©) was proven in the Breast Cancer ...

Statement by Health and Human Services Secretary Donna E. Shalala on the Study of Tamoxifen and Raloxifene
25 May 99 | The National Cancer Institute, through the National Surgical Adjuvant Breast and Bowel Project, begins recruiting postmenopausal women at increased risk of breast cancer to participate in one of the largest breast cancer prevention trials ever ...

Breast Cancer Prevention Study Seeks Volunteers: Study of Tamoxifen and Raloxifene (STAR) Under Way Across North America
25 May 99 | The trial will include 22,000 postmenopausal women at increased risk of breast cancer to determine whether the osteoporosis prevention drug raloxifene (Evista©) is as effective in reducing the chance of developing breast cancer as tamoxifen (...

National Cancer Institute Launches Capital Area SERM Study
20 May 99 | The National Cancer Institute (NCI) has launched the first long-term clinical research study to evaluate the safety of the drug raloxifene (Evista©) in premenopausal women at high risk of breast cancer. Early studies of raloxifene, an ...

Course of Breast Cancer Treatment Differs for Black and White Women
10 May 99 | Researchers from the National Cancer Institute (NCI) have found significant differences in how black and white breast cancer patients are treated during their illness. The BWCSS used age, race, gender, and staging data on breast cancer patients ...

NCI Awards Contract for Geographic Information System To Support Breast Cancer Research on Long Island
07 May 99 | The National Cancer Institute (NCI) announced today the award of a contract to AverStar, Inc., of Vienna, Va., to develop and implement a prototype geographic information system (GIS) for breast cancer studies as part of the Long Island Breast ...

Questions and Answers: NCI's Contract Award for Geographic Information System To Support Breast Cancer Research on Long Island
07 May 99 | 1. What is the Long Island Breast Cancer Study Project (LIBCSP)? The LIBCSP is a multistudy investigation of possible environmental causes of breast cancer in Suffolk, Nassau, and Schoharie counties, N.Y., and in Tolland County, Conn.

Scientists Report Rapid Telomere Shortening in Infants
29 Apr 99 | In the May issue of the journal Blood*, scientists report seeing rapid shortening of telomeres in young, healthy children. Further studies led scientists to propose in 1990 that telomere shortening might be the molecular equivalent of aging ...

Questions and Answers: Annual Report to the Nation on the Status of Cancer, 1973-1996, With a Special Section on Lung Cancer and Tobacco Smoking
20 Apr 99 | The American Cancer Society (ACS), the National Cancer Institute (NCI), and the Centers for Disease Control and Prevention (CDC), including the National Center for Health Statistics (NCHS), collaborated to create this annual report. Prostate ...

Annual Report Shows Continuing Decline in U.S. Cancer Incidence and Death Rates; Special Section Focuses on Lung Cancer and Tobacco Smoking
20 Apr 99 | However, a special section of the study focusing on lung cancer and smoking reports that, unless the increase in adolescent smoking can be reversed, declining lung cancer rates are likely to start increasing again. By far, the greatest decline in...

Research on Cervical Cancer Vaccines
12 Apr 99 | Also under development are "naked DNA" vaccines, created by combining one or more genes that encode HPV surface proteins with plasmid DNA. - National Cancer Institute is testing a virus-like particle from HPV16 in a phase I/II study in people at ...

Childhood Brain Tumors: Facts and Figures
05 Apr 99 | Cancer can spread, or metastasize, to the brain from other parts of the body or it can originate in the brain as a primary brain tumor. Brain tumors account for about 90 percent of all primary central nervous system (CNS) malignancies in children...

NCI Launches New Pediatric Brain Tumor Consortium
05 Apr 99 | The National Cancer Institute (NCI) announced today that it has awarded funds for a Pediatric Brain Tumor Consortium, a network of medical centers that will evaluate promising treatments for children with brain malignancies. "No one children's ...

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