National Cancer Institute

Angiogenesis Inhibitors in Cancer Research
02 Apr 99 | Endothelial cells, the cells that form the walls of blood vessels, are the source of new blood vessels and have a remarkable ability to divide and migrate. Some of the differences between standard chemotherapy and anti-angiogenesis therapy are ...

NCI and Sugen to Collaborate on Development of Anti-Cancer Agent
02 Apr 99 | The National Cancer Institute (NCI) has signed a clinical trials agreement with Sugen, Inc., to collaborate on the development of SU5416, an inhibitor of angiogenesis that has been shown to inhibit the growth of tumors in mice. In Phase I ...

New Project Launched to Study Minority Populations
26 Mar 99 | These cooperative relationships between community-based programs and large research institutions will be used to foster cancer awareness activities, support minority enrollment in clinical trials, and encourage minority scientists to participate ...

NCI and DOD Launch Pilot Project for Coding Cancer Grants
26 Mar 99 | The National Cancer Institute (NCI) and the Department of Defense Office of Congressionally Directed Medical Research Programs (CDMRP), of the U.S. Army Medical Research and Materiel Command, announced this week the launch of a joint pilot program...

NCI Names Two Sites for Early Endostatin Trials
24 Mar 99 | The National Cancer Institute has named two sites for its initial clinical trials of the anti-angiogenesis drug endostatin. They will involve people with advanced solid tumors that include, but which are not limited to, lung cancer lymphoma, ...

Drug Discovery at National Cancer Institute
16 Mar 99 | The National Cancer Institute (NCI) has played an active role in the development of drugs for cancer treatment for over 40 years. NCI's Cancer Therapy Evaluation Program (CTEP), also a part of DCTD, administers clinical drug development.

Scientists Report New Lead in the Genetics of HIV Resistance
11 Mar 99 | Now, a leading group of scientists in the genetics of HIV resistance says it has identified differences in certain immune response genes that show the strongest genetic effect yet on how fast people infected with HIV-1 progress to AIDS *. Slow ...

National Cancer Institute Statement: High-Dose Chemotherapy/ Bone Marrow Transplant Studies for Breast Cancer
10 Mar 99 | The National Cancer Institute (NCI) is sponsoring studies of the effectiveness of high- dose chemotherapy and autologous bone marrow or stem cell transplantation in the treatment of breast cancer. In February, NCI called together a group to ...

Current Status of Research on Simian Virus 40
02 Mar 99 | The largest studies ultimately showed no increase in cancer or cancer-related death among people who were given the SV40-contaminated polio vaccine. But again, the association between SV40 and cancer remained uncertain when other scientists ...

NCI Issues Clinical Announcement on Cervical Cancer: Chemotherapy Plus Radiation Improves Survival
22 Feb 99 | The National Cancer Institute (NCI) today mailed a clinical announcement to thousands of physicians stating that strong consideration should be given to adding chemotherapy to radiation therapy in the treatment of invasive cervical cancer. NCI's ...

Breast Density, Hormone Replacement, and Breast Cancer Risk
16 Feb 99 | Studies, including recently published data from the Postmenopausal Estrogen/Progestin Interventions (PEPI) trial, show that about one-quarter of women who use hormone replacement therapies (HRT) that include progestin have an increase in breast ...

ORI Reports Fabricated and/or Falsified Data for Three Patients on NCI-Sponsored Studies
05 Feb 99 | ORI found that the data manager fabricated and/or falsified data for three individual patients, one in each of three different clinical trials. ORI found that, for three patients, the data manager falsified and/or fabricated telephone contacts ...

NCI's Statement on the IOM Report on the Unequal Burden of Cancer
20 Jan 99 | The Institute of Medicine's (IOM) report on the important issue of the unequal burden of cancer for ethnic minorities and the underserved presents a series of useful findings and recommendations for the National Institutes of Health (NIH) and the ...

National Cancer Institute Research on Causes of Cancers in Children
05 Jan 99 | Among the 12 major types of childhood cancers, leukemias (blood cell cancers) and brain and other central nervous system tumors account for over one-half of the new cases. - Clinical trials to identify superior treatments for childhood cancers, ...

National Cancer Institute Launches Imaging Initiative
08 Dec 98 | Recognizing these tremendous opportunities, the National Cancer Institute will soon launch a forward-looking initiative that will create Centers for In Vivo Cell and Molecular Imaging (CICMIs). These Centers will bridge the gaps between the ...

The Director's Challenge: Toward A Molecular Classification of Tumors
08 Dec 98 | Recognizing the tremendous opportunities that these new technologies provide, the National Cancer Institute (NCI) soon will launch a five-year initiative challenging scientists to apply these tools to tumor cells in order to define their unique ...

Phase II Cancer Vaccine Trial for B-Cell Lymphoma
08 Dec 98 | Since launching the nation's first phase II cancer vaccine trial for B-cell lymphoma in 1994, researchers at the National Cancer Institute (NCI) have vaccinated 21 patients with this common blood-cell tumor that strikes an estimated 41,000 ...

NCI Announces Creation of Early Detection Research Network: Comprehensive Initiative Will Develop and Validate Early Detection Markers for Cancer
08 Dec 98 | A major initiative being under taken by the National Cancer Institute (NCI) will assist in the translation of these discoveries into methods for detecting these warning signals, sometimes even before full-blown cancer can develop, by creating the ...

Leadership Initiative on Cancer to Promote Research in Minority Communities
08 Dec 98 | Recognizing a need to further support cancer control projects focused on special populations, NCI is extending the Leadership Initiative on Cancer to foster cancer awareness and community-based educational activities, and to promote research on ...

Questions and Answers on NCI's Tobacco Research Implementation Plan
19 Nov 98 | Two immediate initiatives are the Transdisciplinary Tobacco Research Centers and the State and Community Tobacco Control Interventions. NCI and NIDA will fund a series of Transdisciplinary Tobacco Research Centers that will study the prevention ...

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