St. Jude Children's Research Hospital (ALSAC)

St. Jude Scientists Develop New System for Generating Influenza A Virus
08 Jun 00 | The St. Jude research group developed a way of producing influenza A strains in the laboratory by manipulating the eight RNA segments of the virus. By this new method, virus is generated by using eight plasmids, or circular pieces of DNA ...

St. Jude Research Study Shows Advances in Gene Therapy Transfer
30 May 00 | (Memphis, Tennessee, May 30, 2000) Researchers at St. Jude Children's Research Hospital have developed new methods that appear to remove certain gene transfer barriers in blood diseases, showing gene transfer rates 10 to 20 times greater than ...

St. Jude Study Reveals Killer Gene Is Silenced in Aggressive Childhood Neuroblastoma
10 May 00 | The research group, led by scientist Vincent Kidd, Ph.D., of the department of Tumor Cell Biology at St. Jude, reported that a large proportion of the tumors from neuroblastoma patients with amplified-MYCN lack the caspase 8 protein. ...

Researchers discover biochemical link between two rare diseases
06 Apr 00 | "My laboratory studies how cells respond to radiation and chemotherapy," said lead researcher Michael Kastan, MD, PhD, chairman of the department of hematology/oncology at St. Jude. "We have shown that ATM is a kinase enzyme and it directly ...

Physicians have better insight on treating patients with Philadelphia chromosome-positive acute lymphoblastic leukemia
06 Apr 00 | St. Jude Children's Research Hospital investigator Ching-Hon Pui, M.D. is one of the authors of the study. The research concluded that bone marrow transplant with a matched sibling donor is the best possible treatment for these patients regardless...

$11 Million Grant Supports Study Of How Genes Affect Cancer Chemotherapy
04 Apr 00 | Understanding variation in the genes that control drug metabolism and toxicity will improve dosing, increasing the benefits of cancer chemotherapy and reduce side effects. The Pharmacogenetics of Anticancer Agents Research (PAAR) Group includes ...

St. Jude Research Study Reveals Mechanisms of Neuron Receptor Function in the Brain
01 Apr 00 | (Memphis, Tennessee, April 1, 2000 ) Research led by developmental neurobiologist Michisuke Yuzaki, M.D., Ph.D., at St. Jude Children's Research Hospital shows how glutamate receptors work between neurons in the brain. This understanding paves ...

Kay Jewelers Announces $1.5 Million Endowment of St. Jude Children's Research Hospital
07 Mar 00 | Sterling store managers were challenged in September to raise funds for St. Jude through the sale of "Cubby," a white plush bear. Sterling announced its partnership with St. Jude at their managers meeting last September, where a moving ...

CountryCool.com Helps WMZQ Raise $1 Million for the Kids of St. Jude
08 Feb 00 | (Washington, D.C., February 8, 2000) CountryCool.com, the leading country music portal on the Web, helped WMZQ, Washington's top country music station, while their loyal listeners made history as they raised a record $1,001,547.00 for St. Jude ...

Newly discovered death signal could hold key to eradicating deadly bacteria
28 Jan 00 | Scientists at St. Jude Children's Research Hospital have discovered a death signal that brings about the death of Streptococcus pneumoniae (also known as pneumococcus) - a discovery that could lead to revolutionary new treatments for the killer ...

Country music industry unites to help children of St. Jude
10 Jan 00 | "Country Cares" grew out of the inspiration of ALABAMA's Owen, who challenged the country music industry to support St. Jude at the Country Radio Seminar in Nashville in 1989. St. Jude and the country radio industry work together with some of the...

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