$44.7 Million Gates Foundation Grant to Evaluate New Strategies to Fight HIV-Related Tuberculosis

Johns Hopkins Medicine
Thursday, 15 July 2004

At the XV International AIDS Conference in Bangkok today, the Bill & Melinda Gates Foundation announced a $44.7 million grant to support the Consortium to Respond Effectively to the AIDS-TB Epidemic (CREATE), which will conduct research on urgently needed strategies to control TB in communities with high HIV infection rates. Nelson Mandela, the former president of South Africa, spoke at the conference in support of the worldwide fight against AIDS and TB.
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CREATE is led by Richard Chaisson, M.D., professor of medicine at The Johns Hopkins University School of Medicine , and includes researchers and health policy experts in Africa, South America, Europe, and the U.S.

"TB and HIV form a lethal combination, each amplifying the other's progress," said Chaisson. "By studying the impact of promising new strategies, we hope to inform critical health policy decisions in countries confronting TB and HIV."

Because HIV weakens the immune system, people with HIV are especially vulnerable to TB, and TB rates have increased significantly in countries with high HIV prevalence. In sub-Saharan Africa, two-thirds of TB patients are co-infected with HIV, and of the estimated 1.6 million deaths caused by TB annually, one quarter occur among people living with HIV/AIDS. TB is now the leading killer of people with HIV worldwide.

For more information about CREATE, the Center for Tuberculosis Research at Johns Hopkins visit tbhiv-create.org and www.hopkins-tb.com

For more information, or to contact Johns Hopkins Medicine, see their website at: www.hopkinsmedicine.org

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